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首页-小分子抑制剂&激动剂-Tyrosine Kinase-VEGFR-MGCD-265 analog
MGCD-265 analog

Chemical Structure : MGCD-265 analog

CAS No.: 875337-44-3

MGCD-265 analog (MGCD265 analog)

货号: PC-42768Not For Human Use, Lab Use Only.

MGCD-265 analog is an analog of MGCD-265, and an orally bioavailable multikinase inhibitor with potential antineoplastic activity with IC50 of 29 nM and 10 nM for c-Met and VEGFR2, respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

MGCD-265 analog is an analog of MGCD-265, and an orally bioavailable multikinase inhibitor with potential antineoplastic activity with IC50 of 29 nM and 10 nM for c-Met and VEGFR2, respectively.

物理化学性质&存储条件

分子量 517.5977
分子式 C26H20FN5O2S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Benzeneacetamide, N-[[[3-fluoro-4-[[2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy]phenyl]amino]thioxomethyl]-

参考文献

1. Claridge S, et al. 2008 May 1;18(9):2793-8.

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