MG-C-30

Chemical Structure : MG-C-30

CAS No.: 877164-43-7

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货号: PC-28379Not For Human Use, Lab Use Only.

MG-C-30 is a small molecule CD27 agonist with EC50 of 0.84 uM in 4-IBB and CD27 reporter cell assays, augments 4-IBB and CD27 signaling in vitro, potentiates the secretion of TNF-α and IFN-γ in PBMCs, activate natural killer cells, delays tumor growth in EG7-OVA tumor-bearing mice.

规格	价格	库存
10 mg	￥980	In stock
25 mg	￥1580	In stock
50 mg	￥2580	In stock
100 mg		Get quote

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生物&药学活性

MG-C-30 is a small molecule CD27 agonist with EC50 of 0.84 uM in 4-IBB and CD27 reporter cell assays, augments 4-IBB and CD27 signaling in vitro, potentiates the secretion of TNF-α and IFN-γ in PBMCs, activate natural killer cells, delays tumor growth in EG7-OVA tumor-bearing mice.

物理化学性质&存储条件

分子量	450.56
分子式	C24H26N4O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(1-(1H-Benzo[d]imidazol-2-yl)-2-methylpropyl)-2-(2-(3,4-dimethoxyphenyl)thiazol-4-yl)acetamide

参考文献

1. Abdel-Rahman SA, et al. Sci Adv. 2024 Oct 18;10(42):eadq5540.

MG-C-30

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MG-C-30

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物理化学性质&存储条件

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