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首页-小分子抑制剂&激动剂-GPCR-Prostaglandin Receptor-MF266-3
MF266-3

Chemical Structure : MF266-3

CAS No.: 244101-03-9

MF266-3 (MF 266-3)

货号: PC-63011Not For Human Use, Lab Use Only.

MF266-3 is a potent, selective prostaglandin E receptor subtype 3 (EP3) antagonist with Ki of 0.8 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    MF266-3 is a potent, selective prostaglandin E receptor subtype 3 (EP3) antagonist with Ki of 0.8 nM.
    MF266-3 displayes a relatively good selectivity over other prostanoid receptors.

    物理化学性质&存储条件

    分子量 570.882
    分子式 C27H21BrClNO4S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (2E)-N-[(5-bromo-2-methoxyphenyl)sulfonyl]-3-[5-chloro-2-(2-naphthylmethyl)phenyl]acrylamide

    参考文献

    1. Clark P. et al. J Pharmacol Exp Ther. 2008 May;325(2):425-34.

    2. Juteau H, et al. Bioorg Med Chem. 2001 Aug;9(8):1977-84.

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