METTL21A-IN-1

首页-小分子抑制剂&激动剂-Epigenetics-Histone Methyltransferase (HMTase)-METTL21A-IN-1

Chemical Structure : METTL21A-IN-1

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货号: PC-27763Not For Human Use, Lab Use Only.

METTL21A-IN-1 (Compound 6d) is a first-in-class, specific inhibitor of protein lysine methyltransferase METTL21A, highly selective against a panel of 44 human MTases.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

METTL21A-IN-1 (Compound 6d) is a first-in-class, specific inhibitor of protein lysine methyltransferase METTL21A, highly selective against a panel of 44 human MTases.
METTL21A is a protein lysine MTase responsible for the trimethylation of HSP70 family members.

物理化学性质&存储条件

分子量	440.34
分子式	C17H15F3N6O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxy-N-(3-(trifluoromethoxy)phenyl)tetrahydrofuran-2-carboxamide

参考文献

1. Kocek H, et al. Eur J Med Chem. 2026 Aug 11;319:119227.

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METTL21A-IN-1

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