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首页-小分子抑制剂&激动剂-GPCR-Bradykinin Receptor-MEN 11270
MEN 11270

Chemical Structure : MEN 11270

CAS No.: 235082-52-7

MEN 11270 (MEN-11270, MEN11270)

货号: PC-26630Not For Human Use, Lab Use Only.

MEN 11270 is a high affinity, selective peptide antagonist of type 2 bradykinin receptor (B2R) with pKi of 10.3, >10,000-fold selective over Kinin B1 receptor (B1R).

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

MEN 11270 is a high affinity, selective peptide antagonist of type 2 bradykinin receptor (B2R) with pKi of 10.3, >10,000-fold selective over Kinin B1 receptor (B1R).

物理化学性质&存储条件

分子量 1299.55
分子式 C60H90N20O11S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

L-Arginine, D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-(2S)-2,4-diaminobutanoyl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-, (10→7)-lactam

参考文献

1. Meini S, et al. J Pharmacol Exp Ther. 1999 Jun;289(3):1250-6.

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