MEKK2 inhibitor 1s | Probechem Biochemicals

首页-小分子抑制剂&激动剂-Ras-Raf-MAPK-ERK Pathway-MEKK (MAP3K)-MEKK2 inhibitor 1s

Chemical Structure : MEKK2 inhibitor 1s

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MEKK2 inhibitor 1s (MEKK2-IN-1s)

货号: PC-62541Not For Human Use, Lab Use Only.

MEKK2 inhibitor 1s (MEKK2-IN-1s) is a potent MEKK2 (MAP3K2) inhibitor with IC50 of 16 nM, inhibits MEKK2 and MEKK3 with similar potencies.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

MEKK2 inhibitor 1s (MEKK2-IN-1s) is a potent MEKK2 (MAP3K2) inhibitor with IC50 of 16 nM, inhibits MEKK2 and MEKK3 with similar potencies.
MEKK2 inhibitor 1s displays activity in cell-based assays in which it inhibited ERK5 pathway activation in cells and inhibited cell migration in a scratch assay.

物理化学性质&存储条件

分子量	338.363
分子式	C19H18N2O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(Z)-8-ethoxy-2-((4-hydroxy-2-methylphenyl)imino)-2H-chromene-3-carboxamide

参考文献

1. Ahmad S, et al. Biochem Biophys Res Commun. 2018 Jan 29;496(1):205-211.

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MEKK2 inhibitor 1s (MEKK2-IN-1s)

生物&药学活性

物理化学性质&存储条件

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MEKK2 inhibitor 1s (MEKK2-IN-1s)

生物&药学活性

物理化学性质&存储条件

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