MEK4 inhibitor 6ff

Chemical Structure : MEK4 inhibitor 6ff

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货号: PC-72695Not For Human Use, Lab Use Only.

MEK4 inhibitor 6ff is potent, selective MEK4 inhibitor with IC50 of 66 nM.

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生物&药学活性

MEK4 inhibitor 6ff is potent, selective MEK4 inhibitor with IC50 of 66 nM.
MEK4 inhibitor 6ff displays excellent selectivity across the entire MEK family, 150-fold more potent against MEK4 than any other MEKkinase, and is at least 385-fold selective against three other MEK kinases.

物理化学性质&存储条件

分子量	256.236
分子式	C14H9FN2O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(6-fluoro-2H-indazol-3-yl)benzoic acid

参考文献

1. Kristine K Deibler, et al. ChemMedChem. 2019 Mar 22;14(6):615-620.