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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-iGluR-MDL-29951
MDL-29951

Chemical Structure : MDL-29951

CAS No.: 130798-51-5

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MDL-29951 (MDL 29,951, MDL29951)

货号: PC-23317Not For Human Use, Lab Use Only.

MDL-29951 (MDL-29, 951) is a potent glycine antagonist of NMDA receptor with Ki of 0.14 uM for [3H]glycine binding in vitro, also is a potent GPR17 agonist with pEC50 of 6.48.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

MDL-29951 (MDL-29, 951) is a potent glycine antagonist of NMDA receptor with Ki of 0.14 uM for [3H]glycine binding in vitro, also is a potent GPR17 agonist with pEC50 of 6.48.

物理化学性质&存储条件

分子量 302.11
分子式 C12H9Cl2NO4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3-(2-Carboxyethyl)-4,6-dichloro-1H-indole-2-carboxylic acid

参考文献

1. Baron BM, et al. J Pharmacol Exp Ther. 1992 Sep;262(3):947-56.

2. Wright SW, et al. Bioorg Med Chem Lett. 2003 Jun 16;13(12):2055-8.

3. Stephanie Hennen, et al. Sci Signal. 2013 Oct 22;6(298):ra93.

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