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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Plasminogen Activator Inhibitor-1 (PAI-1)-MDI-2268
MDI-2268

Chemical Structure : MDI-2268

CAS No.: 1609176-50-2

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MDI-2268 (MDI2268)

货号: PC-35871Not For Human Use, Lab Use Only.

MDI-2268 (MDI2268) is a small-molecule, in vivo-active inhibitor of plasminogen activator inhibitor type-1 (PAI-1), demonstrates excellent pharmacokinetics, potent activity against vitronectin-bound PAI-1 in vivo, and efficacy in murine model of venous thrombosis.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    MDI-2268 (MDI2268) is a small-molecule, in vivo-active inhibitor of plasminogen activator inhibitor type-1 (PAI-1), demonstrates excellent pharmacokinetics, potent activity against vitronectin-bound PAI-1 in vivo, and efficacy in murine model of venous thrombosis.

    物理化学性质&存储条件

    分子量 277.203
    分子式 C10H10F3N3O3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    2-hydrazinyl-2-oxo-N-(3-(trifluoromethoxy)benzyl)acetamide

    参考文献

    1. Reinke AA, et al. J Biol Chem. 2018 Dec 3. pii: jbc.RA118.004885. doi: 10.1074/jbc.RA118.004885.

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