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首页-小分子抑制剂&激动剂-Epigenetics-Sirtuin -MC3215
MC3215

Chemical Structure : MC3215

CAS No.: 2848613-22-7

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MC3215

货号: PC-25602Not For Human Use, Lab Use Only.

MC3215 is a specific, cellular active small molecule activator of mitochondrial SIRT5 with binding KD of 28 uM, increases in vitro Sirt5 deacetylase activity and elicits similar effects to Sirt5 overexpression.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

MC3215 is a specific, cellular active small molecule activator of mitochondrial SIRT5 with binding KD of 28 uM, increases in vitro Sirt5 deacetylase activity and elicits similar effects to Sirt5 overexpression.

物理化学性质&存储条件

分子量 411.47
分子式 C22H21NO5S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

diethyl 1-benzoyl-4-(thiophen-3-yl)-1,4-dihydropyridine-3,5-dicarboxylate

参考文献

1. Suenkel B, et al. J Med Chem. 2022 Oct 27;65(20):14015-14031.

2. Carola Castiello, et al. Drug Des Devel Ther. 2025 Jun 27:19:5489-5505.

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