MC-100093 | GLT-1 modulator | Probechem Biochemicals

Chemical Structure : MC-100093

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MC-100093 (MC100093)

货号: PC-72279Not For Human Use, Lab Use Only.

MC-100093 (MC100093) is a potent, orally bioavailable upregulator of glutamate transporter-1 (GLT-1) and devoid of antimicrobial properties.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

MC-100093 (MC100093) is a potent, orally bioavailable upregulator of glutamate transporter-1 (GLT-1) and devoid of antimicrobial properties.
MC-100093 enhanced uptake of glutamate into astrocytes in a mouse neuron/astrocyte co-culture model with IC50 of 0.1 uM.
MC-100093 restored the expression of NA core GLT-1.
MC-100093 (50 mg/kg) attenuated cue-primed relapse to cocaine-seeking without reducing motivation to consume regular chow or sucrose pellets or affecting body weight.

物理化学性质&存储条件

分子量	269.345
分子式	C13H23N3O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(3S,4R)-3-((R)-1-hydroxyethyl)-4-((R)-1-(4-methylpiperazin-1-yl)-1-oxopropan-2-yl)azetidin-2-one

参考文献

1. Lori A Knackstedt, et al. J Pharmacol Exp Ther. 2021 Aug;378(2):51-59.

MC-100093 (MC100093)

生物&药学活性

物理化学性质&存储条件

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MC-100093 (MC100093)

生物&药学活性

物理化学性质&存储条件

参考文献

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