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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Bacterial-MBX3132
MBX3132

Chemical Structure : MBX3132

CAS No.: 1636878-33-5

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MBX3132 (MBX 3132)

货号: PC-72797Not For Human Use, Lab Use Only.

MBX3132 is a small mocule inhibitor of AcrB multidrug efflux pump, fully potentiates the activity of a broad range of antibiotics at 0.1 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    MBX3132 is a small mocule inhibitor of AcrB multidrug efflux pump, fully potentiates the activity of a broad range of antibiotics at 0.1 uM.
    MBX3132 does not exhibit membrane-disrupting or antibacterial activity.

    物理化学性质&存储条件

    分子量 494.654
    分子式 C27H34N4O3S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N-(4-(2-((5-cyano-8-(2,6-dimethylmorpholino)-3,3-dimethyl-3,4-dihydro-1H-pyrano[3,4-c]pyridin-6-yl)thio)ethyl)phenyl)acetamide

    参考文献

    1. Hanno Sjuts, et al. Proc Natl Acad Sci U S A. 2016 Mar 29; 113(13): 3509–3514.

    2. Coline Plé, et al. Nat Commun. 2022 Jan 10;13(1):115.

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