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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Bacterial-MBX1641
MBX1641

Chemical Structure : MBX1641

CAS No.: 329694-16-8

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MBX1641 (MBX-1641)

货号: PC-27561Not For Human Use, Lab Use Only.

MBX1641 (MBX-1641) is a small-molecule inhibitor of bacterial type III secretion (TTS, T3SS), not only bind effectively with YspD, but also bind to the functionally important domains of YspD and might lead to the functional inactivation of YspD, inhibits TIIISS effector protein ExoS in P. aeruginosa.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

MBX1641 (MBX-1641) is a small-molecule inhibitor of bacterial type III secretion (TTS, T3SS), not only bind effectively with YspD, but also bind to the functionally important domains of YspD and might lead to the functional inactivation of YspD, inhibits TIIISS effector protein ExoS in P. aeruginosa.

物理化学性质&存储条件

分子量 368.21
分子式 C17H15Cl2NO4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(benzo[d][1,3]dioxol-5-ylmethyl)-2-(2,4-dichlorophenoxy)propanamide

参考文献

1. Duncan MC, et al. Antimicrob Agents Chemother. 2014;58(2):1118-26.

2. Aburto-Rodríguez NA, et al. Molecules. 2021 Dec 16;26(24):7635.

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