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首页-小分子抑制剂&激动剂-Apoptosis-MDM2-p53-MB710
MB710

Chemical Structure : MB710

CAS No.: 2230044-57-0

MB710 (MB-710)

货号: PC-35309Not For Human Use, Lab Use Only.

MB710 is a small-molecule p53 mutant Y220C stabilizer, binds tightly to the Y220C pocket and stabilizes p53-Y220C in vitro..

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    MB710 is a small-molecule p53 mutant Y220C stabilizer, binds tightly to the Y220C pocket and stabilizes p53-Y220C in vitro.

    物理化学性质&存储条件

    分子量 457.286
    分子式 C16H16IN3O3S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    2-(diethylamino)-5-hydroxy-6-iodo-7-(1H-pyrrol-1-yl)benzo[d]thiazole-4-carboxylic acid

    参考文献

    1. Baud MGJ, et al. Eur J Med Chem. 2018 May 25;152:101-114.

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