MB710 | p53 Y220C reactivator | Probechem Biochemicals

Chemical Structure : MB710

CAS No.: 2230044-57-0

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货号: PC-35309Not For Human Use, Lab Use Only.

MB710 is a small-molecule p53 mutant Y220C stabilizer, binds tightly to the Y220C pocket (Kd=4 uM) and stabilizes p53-Y220C in vitro.

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MB710 is a small-molecule p53 mutant Y220C stabilizer, binds tightly to the Y220C pocket (Kd=4 uM) and stabilizes p53-Y220C in vitro.

分子量	457.286
分子式	C16H16IN3O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(diethylamino)-5-hydroxy-6-iodo-7-(1H-pyrrol-1-yl)benzo[d]thiazole-4-carboxylic acid

1. Baud MGJ, et al. Eur J Med Chem. 2018 May 25;152:101-114.