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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-nAChR-MB327
MB327

Chemical Structure : MB327

CAS No.: 61368-98-7

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MB327

货号: PC-22398Not For Human Use, Lab Use Only.

MB327 is an antinicotinic bispyridinium compound, restores functional activity of nAChR. MB327 could restore soman-impaired neuromuscular function in vitro and improve survival of sarin, soman and tabun poisoned guinea pigs in vivo.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

MB327 is an antinicotinic bispyridinium compound, restores functional activity of nAChR. MB327 could restore soman-impaired neuromuscular function in vitro and improve survival of sarin, soman and tabun poisoned guinea pigs in vivo.

物理化学性质&存储条件

分子量 566.31
分子式 C21H32I2N2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1,1'-(propane-1,3-diyl)bis(4-(tert-butyl)pyridin-1-ium) iodide

参考文献

1. Rappenglück S, et al. ChemMedChem. 2018 Sep 6;13(17):1806-1816.

2. Price ME, et al. Toxicol Lett. 2018 Sep 1;293:167-171.

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