MAX10181 | PD-L1 inhibitor | Probechem Biochemicals

Chemical Structure : MAX10181

CAS No.: 2171558-14-6

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MAX10181 (MAX-10181)

货号: PC-20279Not For Human Use, Lab Use Only.

MAX10181 (MAX-10181) is an orally active small molecule PD-L1 inhibitor, shows similar efficacy as Durvalumab in the head to head test of human PD-L1 knock-in MC38 cell line in human PD-1 knock-in mice.

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5 mg	￥2780	In stock
10 mg	￥4380	In stock
25 mg	￥7280	In stock
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100 mg		Get quote

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生物&药学活性

MAX10181 (MAX-10181) is an orally active small molecule PD-L1 inhibitor, shows similar efficacy as Durvalumab in the head to head test of human PD-L1 knock-in MC38 cell line in human PD-1 knock-in mice.

物理化学性质&存储条件

分子量	527.54
分子式	C29H28F3NO5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-2-((3-(3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-methylstyryl)-4-(trifluoromethyl)benzyl)amino)-3-hydroxy-2-methylpropanoic acid

参考文献

1. Yuguang Wang, et al. Cancer Res (2019) 79 (13_Supplement): LB-018.

MAX10181 (MAX-10181)

生物&药学活性

物理化学性质&存储条件

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MAX10181 (MAX-10181)

生物&药学活性

物理化学性质&存储条件

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