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首页-小分子抑制剂&激动剂-Others-Other Targets-MAT2A inhibitor ZS97
MAT2A inhibitor ZS97

Chemical Structure : MAT2A inhibitor ZS97

CAS No.: 3106086-13-6

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MAT2A inhibitor ZS97

货号: PC-27635Not For Human Use, Lab Use Only.

MAT2A inhibitor ZS97 is a potent, selective and orally bioavailable methionine adenosyltransferase 2A (MAT2A) inhibitor, demonstrates potent enzymatic inhibition, effectively depleting intracellular SAM and suppressing downstream PRMT5-mediated methylation.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

MAT2A inhibitor ZS97 is a potent, selective and orally bioavailable methionine adenosyltransferase 2A (MAT2A) inhibitor, demonstrates potent enzymatic inhibition, effectively depleting intracellular SAM and suppressing downstream PRMT5-mediated methylation.

物理化学性质&存储条件

分子量 410.23
分子式 C18H12BrN5O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4-bromo-6-(1H-indazol-4-yl)-9-(methylamino)furo[2,3-f]quinazolin-7(6H)-one

参考文献

1. Lin L, et al. J Med Chem. 2026 Aug 13;69(15):18838-18855.

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