MAP855 | MEK1/2 inhibitor | Probechem Biochemicals

Chemical Structure : MAP855

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MAP855 (MAP-855)

货号: PC-72697Not For Human Use, Lab Use Only.

MAP855 (MAP-855) is a highly potent, selective, ATP-competitive MEK1/2 inhibitor (pERK IC50=5 nM) with equipotent inhibition of WT and mutant MEK1/2.

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生物&药学活性

MAP855 (MAP-855) is a highly potent, selective, ATP-competitive MEK1/2 inhibitor (pERK IC50=5 nM) with equipotent inhibition of WT and mutant MEK1/2.

物理化学性质&存储条件

分子量	564.978
分子式	C28H23ClF2N6O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-((3S,4S)-4-(8-(2-chloro-4-(pyrimidin-2-yloxy)phenyl)-7-fluoro-2-methyl-1H-imidazo[4,5-c]quinolin-1-yl)-3-fluoropiperidin-1-yl)-2-hydroxyethan-1-one

参考文献

1. Poddutoori R, et al. Med Chem. 2022 Feb 23.

MAP855 (MAP-855)

生物&药学活性

物理化学性质&存储条件

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MAP855 (MAP-855)

生物&药学活性

物理化学性质&存储条件

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