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首页-小分子抑制剂&激动剂-Ras-Raf-MAPK-ERK Pathway-MAP4K-MAP4K4-IN-44
MAP4K4-IN-44

Chemical Structure : MAP4K4-IN-44

CAS No.: 1623464-28-7

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MAP4K4-IN-44

货号: PC-62937Not For Human Use, Lab Use Only.

MAP4K4-IN-44 is a potent, moderately selective small molecule MAP4K4 inhibitor with IC50 of 5 nM in LC3K assay, demonstrates favorable in vivo bioavailability in mouse.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    MAP4K4-IN-44 is a potent, moderately selective small molecule MAP4K4 inhibitor with IC50 of 5 nM in LC3K assay, demonstrates favorable in vivo bioavailability in mouse.

    物理化学性质&存储条件

    分子量 349.398
    分子式 C18H19N7O
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    2-methyl-1-(4-(4-(pyridin-4-ylamino)pyrrolo[2,1-f][1,2,4]triazin-6-yl)-1H-pyrazol-1-yl)propan-2-ol

    参考文献

    1. Wang L, et al. Bioorg Med Chem Lett. 2014 Sep 15;24(18):4546-4552.

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