MAP4K4-IN-37 |CAS:2089334-01-8 Probechem Biochemicals

Chemical Structure : MAP4K4-IN-37

加入收藏

MAP4K4-IN-37

货号: PC-35005Not For Human Use, Lab Use Only.

MAP4K4-IN-37 is a potent, selective, orally active inhibitor of serine-threonine kinase MAP4K4 with IC50 of 0.4 nM.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

MAP4K4-IN-37 is a potent, selective, orally active inhibitor of serine-threonine kinase MAP4K4 with IC50 of 0.4 nM.
MAP4K4-IN-37 inhibits the other kinase family members, MINK and TNIK (IC50 of 1.3 and <0.6 nM).
MAP4K4-IN-37 possesses a high degree of kinome selectivity against a set of 244 kinases.
MAP4K4-IN-37 shows potent cellular potency with IC50 of 222 nM, exhibits substantial suppression of TNFα release on LPS-induced TNFα levels in male C57-BL/6J mice

物理化学性质&存储条件

分子量	382.844
分子式	C21H19ClN2O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-{4-[6-Amino-5-(4-chlorophenyl)pyridin-3-yl]phenoxy}-2-methylpropanoic acid

参考文献

1. Dow RL, et al. J Med Chem. 2018 Apr 12;61(7):3114-3125.

MAP4K4-IN-37

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

MAP4K4-IN-37

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.