MAP4K4-IN-17 |CAS:1811510-58-3 Probechem Biochemicals

Chemical Structure : MAP4K4-IN-17

CAS No.: 1811510-58-3

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MAP4K4-IN-17

货号: PC-62935Not For Human Use, Lab Use Only.

MAP4K4-IN-17 is a potent and highly selective MAP4K4 inhibitor with IC50 of 14.9 nM, showes improved overall drug-like properties compared to PF-06260933.

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25 mg	￥1380	In stock
50 mg	￥2280	In stock
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生物&药学活性

MAP4K4-IN-17 is a potent and highly selective MAP4K4 inhibitor with IC50 of 14.9 nM, showes improved overall drug-like properties compared to PF-06260933.
MAP4K4-IN-17 is a lead compound for advanced preclinical development.

物理化学性质&存储条件

分子量	297.746
分子式	C15H12ClN5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	5-(6-amino-5-(4-chlorophenyl)pyridin-3-yl)pyrimidin-2-amine

参考文献

1. Ammirati M, et al. ACS Med Chem Lett. 2015 Oct 6;6(11):1128-33.

MAP4K4-IN-17

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