MAP4K4-IN-11e |CAS:1774346-60-9 Probechem Biochemicals

Chemical Structure : MAP4K4-IN-11e

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MAP4K4-IN-11e (MAP4K4 inhibitor 11e)

货号: PC-61165Not For Human Use, Lab Use Only.

MAP4K4-IN-11e is a potent, selective, ATP-competitive inhibitor of MAP4K4 with IC50 of 1.9 uM, without effect on other stress pathway related kinases.

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生物&药学活性

MAP4K4-IN-11e is a potent, selective, ATP-competitive inhibitor of MAP4K4 with IC50 of 1.9 uM, without effect on other stress pathway related kinases.
MAP4K4 is active at much lower concentration in the cellular neurite outgrowth assay and may exhibit better pharmacokinetic properties.

物理化学性质&存储条件

分子量	301.342
分子式	C17H19NO4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-hexanoyl-4-hydroxy-5-(4-hydroxyphenyl)pyridin-2(1H)-one

参考文献

1. Schröder P, et al. Angew Chem Int Ed Engl. 2015 Oct 12;54(42):12398-403.

MAP4K4-IN-11e (MAP4K4 inhibitor 11e)

生物&药学活性

物理化学性质&存储条件

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MAP4K4-IN-11e (MAP4K4 inhibitor 11e)

生物&药学活性

物理化学性质&存储条件

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