MALT1 inhibitor 8

Chemical Structure : MALT1 inhibitor 8

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货号: PC-49479Not For Human Use, Lab Use Only.

MALT1 inhibitor 8 is a potent, selective and orally bioavailable MALT1 inhibitor with cellular IC50 of 3.2 uM, binds to an induced allosteric site in MALT1.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

MALT1 inhibitor 8 is a potent, selective and orally bioavailable MALT1 inhibitor with cellular IC50 of 3.2 uM, binds to an induced allosteric site in MALT1.

物理化学性质&存储条件

分子量	412.805
分子式	C16H16ClF3N8
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(1s,4s)-N1-(3-chloro-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-N4-(2-(trifluoromethyl)pyrimidin-4-yl)cyclohexane-1,4-diamine

参考文献

1. Stefan Schiesser, et al. Eur J Med Chem. 2022 Jan 5;227:113925.