MAD2L2 inhibitor C3 (C#3, ZINC25496030)

Chemical Structure : MAD2L2 inhibitor C3

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货号: PC-27690Not For Human Use, Lab Use Only.

MAD2L2 inhibitor C#3 (ZINC25496030) is a small-molecule inhibitor of DNA polymerase Pol ζ (zeta) regulatory subunit MAD2L2 (Rev7), disrupts the MAD2L2-Rev1 interaction, potentially causes mutagenic translesion synthesis (TLS) inhibition, sensitizes lung cancer cell lines to cisplatin.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

MAD2L2 inhibitor C#3 (ZINC25496030) is a small-molecule inhibitor of DNA polymerase Pol ζ (zeta) regulatory subunit MAD2L2 (Rev7), disrupts the MAD2L2-Rev1 interaction, potentially causes mutagenic translesion synthesis (TLS) inhibition, sensitizes lung cancer cell lines to cisplatin.

物理化学性质&存储条件

分子量	342.35
分子式	C18H18N2O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2R)-2-(2-(2-(furan-2-yl)-5-methyl-4,5-dihydrooxazol-4-yl)acetamido)-2-phenylacetic acid

参考文献

1. Pernicone N, et al. (2022) Molecules 27 (3), 636.

2. Ayiku PJ, et al. Front Cell Dev Biol. 2026 Jul 29;14:1859193.