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首页-小分子抑制剂&激动剂-Cytoskeleton/Cell Adhesion Molecules-Kinesin-MAC1
MAC1

Chemical Structure : MAC1

CAS No.: 325970-42-1

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MAC1 (Monastrol Antagonizing Compound 1)

货号: PC-62405Not For Human Use, Lab Use Only.

MAC1 (Monastrol Antagonizing Compound 1) is a small molecule that can rescue spindle bipolarity in cells lacking Eg5 activity.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    MAC1 (Monastrol Antagonizing Compound 1) is a small molecule that can rescue spindle bipolarity in cells lacking Eg5 activity.
    MAC1 induces the formation of additional microtubule nucleation centers, which allows kinesin Kif15-dependent bipolar spindle assembly in the absence of Eg5 activity.

    物理化学性质&存储条件

    分子量 247.338
    分子式 C15H21NO2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (E)-1-(1-hydroxycyclohexyl)-3-phenylpropan-1-one oxime

    参考文献

    1. Al-Obaidi N, et al. ACS Chem Biol. 2016 Jun 17;11(6):1544-51.

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