M4K2306

Chemical Structure : M4K2306

加入收藏

货号: PC-22016Not For Human Use, Lab Use Only.

M4K2306 is a potent, selective BMP type I receptor ALK2 inhibitor with IC50 of 7 nM, >500-fold selective over ALK5.

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
200 mg		Get quote
1 g		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

M4K2306 is a potent, selective BMP type I receptor ALK2 inhibitor with IC50 of 7 nM, >500-fold selective over ALK5.
M4K2306 shows cell IC50 of 18 nM in NanoBRET target engagement assay.
M4K2306 also shows high selectivity over ALK1 and ALK6, ALK4, as well as favorable kinome-wide selectivity.
M4K2306 demonstrates excellent kinome-wide selectivity, inhibiting only 3% of 422 kinases by more than 50% at 1 uM.

物理化学性质&存储条件

分子量	474.61
分子式	C28H34N4O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	6-methyl-9-(4-methylpiperazin-1-yl)-4-(3,4,5-trimethoxyphenyl)-6,7-dihydro-5H-benzo[c]pyrido[3,4-e]azepine

参考文献

1. González-Álvarez H, et al. J Med Chem. 2024 Mar 18.

M4K2306

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

M4K2306

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.