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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Calcium Channel -M201-A
M201-A

Chemical Structure : M201-A

CAS No.: 1868231-87-1

M201-A

货号: PC-22420Not For Human Use, Lab Use Only.

M201-A is a potent, selective ryanodine receptor 2 (RyR2) inhibitor, significantly reduces the diastolic Ca2+ in isolated rat ventricular cardiomyocytes, exhibits positive lusi-inotropic effects on rat heart.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

M201-A is a potent, selective ryanodine receptor 2 (RyR2) inhibitor, significantly reduces the diastolic Ca2+ in isolated rat ventricular cardiomyocytes, exhibits positive lusi-inotropic effects on rat heart.

物理化学性质&存储条件

分子量 440.60
分子式 C25H32N2O3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-4-[3-(4-benzylpiperidin-1-yl)propanoyl]-7-methoxy-2,3,4,5-tetrahydro-1,4-benzothiazepine-1-oxide

参考文献

1. Noboru Kaneko, et al. Br J Pharmacol. 2024 May 21. doi: 10.1111/bph.16379.

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