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首页-小分子抑制剂&激动剂-GPCR-Galanin Receptor-M1145
M1145

Chemical Structure : M1145

CAS No.: 1172089-00-7

M1145

货号: PC-23336Not For Human Use, Lab Use Only.

M1145 is a chimeric peptide, potent, selective galanin receptor type 2 (GALR2) agonist with Ki of 6.55 nM, >50-fold selective over GALR1 (Ki=587 nM) and GALR3 (Ki=497 nM).

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

M1145 is a chimeric peptide, potent, selective galanin receptor type 2 (GALR2) agonist with Ki of 6.55 nM, >50-fold selective over GALR1 (Ki=587 nM) and GALR3 (Ki=497 nM).

物理化学性质&存储条件

分子量 2774.23
分子式 C128H205N37O32
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

L-Arginylglycyl-L-arginylglycyl-L-asparaginyl-L-tryptophyl-L-threonyl-L-leucyl-L-asparaginyl-L-seryl-L-alanylglycyl-L-tyrosyl-L-leucyl-L-leucylglycyl-L-prolyl-L-valyl-L-leucyl-L-prolyl-L-prolyl-L-prolyl-L-alanyl-L-leucyl-L-alanyl-L-leucyl-L-alaninamide

参考文献

1. Runesson J, et al. A novel GalR2-specific peptide agonist. Neuropeptides. 2009;43(3):187-192.

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