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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-TRP Channel-M085
M085

Chemical Structure : M085

CAS No.:

M085 (TRPC3/6/7 activator 4o)

货号: PC-21344Not For Human Use, Lab Use Only.

M085 (TRPC3/6/7 activator 4o) is a potent and selective TRPC3/6/7 activator with EC50 of 4.66 uM, also activates hTRPC6 with EC50 of 3.8 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

M085 (TRPC3/6/7 activator 4o) is a potent and selective TRPC3/6/7 activator with EC50 of 4.66 uM, also activates hTRPC6 with EC50 of 3.8 uM.

物理化学性质&存储条件

分子量 398.44
分子式 C21H23FN4O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-(3-(4-fluorophenyl)-7-hydroxy-2-methylpyrazolo[1,5-a]pyrimidin-5-yl)piperidin-1-yl propionate

参考文献

1. Qu C., et al. J. Med. Chem. 2017;60:4680–4692.

2. Yang PL, et al. J Biol Chem. 2021 Oct;297(4):101125.

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