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首页-小分子抑制剂&激动剂-GPCR-Cholecystokinin Receptor-Lyz-866
Lyz-866

Chemical Structure : Lyz-866

CAS No.: 2923120-29-8

Lyz-866

货号: PC-25771Not For Human Use, Lab Use Only.

Lyz-866 is a potent, selective Gi-biased agonist of cholecystokinin (CCK) B receptor (CCKBR) with EC50 of 0.27 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Lyz-866 is a potent, selective Gi-biased agonist of cholecystokinin (CCK) B receptor (CCKBR) with EC50 of 0.27 nM.

物理化学性质&存储条件

分子量 717.64
分子式 C31H37BrN6O7S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-3-((S)-2-((S)-2-acetamido-3-(1H-indol-3-yl)propanamido)-4-(methylthio)butanamido)-4-(((S)-1-amino-3-(3-bromophenyl)-1-oxopropan-2-yl)amino)-4-oxobutanoic acid

参考文献

1. Wang JL, et al. Cell. 2025 Nov 20:S0092-8674(25)01238-3.

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