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首页-小分子抑制剂&激动剂-GPCR-Melatonin Receptor-Luzindole
Luzindole

Chemical Structure : Luzindole

CAS No.: 117946-91-5

Luzindole (N-0774, N0774)

货号: PC-23430Not For Human Use, Lab Use Only.

Luzindole (N-0774) is a potent, selective melatonin receptor antagonist with Ki of 10.2 nM and 158 nM for human MT2 and MT1, respectively.

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5 mg ¥1480 In stock
10 mg ¥2180 In stock
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50 mg ¥5980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Luzindole (N-0774) is a potent, selective melatonin receptor antagonist with Ki of 10.2 nM and 158 nM for human MT2 and MT1, respectively.
Luzindole (N-0774) shows anti-immobility effect and exerts antidepressant-like activity in the C3H/HeN mouse by antagonizing the action of endogenous hormone.

物理化学性质&存储条件

分子量 292.38
分子式 C19H20N2O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(2-(2-Benzyl-1H-indol-3-yl)ethyl)acetamide

参考文献

1. Dubocovich ML, et al. Eur J Pharmacol. 1990 Jul 3;182(2):313-25.

2. Dubocovich ML. J Pharmacol Exp Ther. 1988 Sep;246(3):902-10.

3. Constantinescu CS, et al. 1997;65(4):190-4.

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