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首页-小分子抑制剂&激动剂-Immunology/Inflammation-Thrombopoietin Receptor (CD110)-Lusutrombopag
Lusutrombopag

Chemical Structure : Lusutrombopag

CAS No.: 1110766-97-6

Lusutrombopag (S-888711, S888711)

货号: PC-45744Not For Human Use, Lab Use Only.

Lusutrombopag (S888711) is an orally bioavailable, small molecule thrombopoietin (TPO) receptor agonist.

规格 价格 库存 数量
5 mg ¥1280 In stock
10 mg ¥1880 In stock
25 mg ¥2980 In stock
50 mg ¥4880 In stock
100 mg Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Lusutrombopag (S888711) is an orally bioavailable, small molecule thrombopoietin (TPO) receptor agonist.
Lusutrombopag acts selectively on the human thrombopoietin receptor and activates signal transduction pathways that promote the proliferation and differentiation of bone marrow cells into megakaryocytes, thereby increasing platelet levels.

物理化学性质&存储条件

分子量 591.5458
分子式 C29H32Cl2N2O5S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 33 mg/mL

Chemical Name/SMILES

2-Propenoic acid, 3-[2,6-dichloro-4-[[[4-[3-[(1S)-1-(hexyloxy)ethyl]-2-methoxyphenyl]-2-thiazolyl]amino]carbonyl]phenyl]-2-methyl-, (2E)-

参考文献

1. Kim ES. Drugs. 2016 Jan;76(1):155-8.

2. Sakamaki A, et al. Clin J Gastroenterol. 2017 Jun;10(3):261-264.

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