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首页-小分子抑制剂&激动剂-Immunology/Inflammation-Cyclooxygenase (COX)-Lornoxicam
Lornoxicam

Chemical Structure : Lornoxicam

CAS No.: 70374-39-9

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Lornoxicam (Chlortenoxicam, Ro 13-9297)

货号: PC-27811Not For Human Use, Lab Use Only.

Lornoxicam (Chlortenoxicam, Ro 13-9297) is a highly potent antirheumatic agent and nonsteroidal anti-inflammatory drug (NSAID), shows inhibition of cyclooxygenase COX-1 and COX-2 with IC50 of 5 nM and 8 nM respectively.

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1 g ￥780 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Lornoxicam (Chlortenoxicam, Ro 13-9297) is a highly potent antirheumatic agent and nonsteroidal anti-inflammatory drug (NSAID), shows inhibition of cyclooxygenase COX-1 and COX-2 with IC50 of 5 nM and 8 nM respectively.

物理化学性质&存储条件

分子量 371.81
分子式 C13H10ClN3O4S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

6-Chloro-4-hydroxy-2-methyl-N-(pyridin-2-yl)-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide

参考文献

1. Dittrich P, et al. Drugs Exp Clin Res. 1990;16(2):57-62.

2. Yin J, et al. Br J Ophthalmol. 2008 Apr;92(4):562-8.

3. Berg J, et al. Inflamm Res. 1999 Jul;48(7):369-79.

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