Lopinavir | HIV-1 protease inhibitor | Probechem Biochemicals

Chemical Structure : Lopinavir

CAS No.: 192725-17-0

加入收藏

Lopinavir (ABT-378, ABT378)

货号: PC-21700Not For Human Use, Lab Use Only.

Lopinavir (ABT-378) is a highly potent inhibitor of HIV-1 protease with Ki of 1.3 to 3.6 pM for wild-type and mutant HIV protease.

规格	价格	库存
50 mg	￥880	In stock
100 mg	￥1280	In stock
200 mg	￥1880	In stock
1 g		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

Lopinavir (ABT-378) is a highly potent inhibitor of HIV-1 protease with Ki of 1.3 to 3.6 pM for wild-type and mutant HIV protease.
Lopinavir (ABT-378) blocks the replication of laboratory and clinical strains of HIV type 1 (50% effective concentration [EC50], 0.006 to 0.017 microM).
Lopinavir (ABT-378) maintains high potency against mutant HIV selected by ritonavir in vivo (EC50,

物理化学性质&存储条件

分子量	628.81
分子式	C37H48N4O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-N-((2S,4S,5S)-5-(2-(2,6-Dimethylphenoxy)acetamido)-4-hydroxy-1,6-diphenylhexan-2-yl)-3-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanamide

参考文献

1. Sham HL, et al. Antimicrob Agents Chemother. 1998 Dec;42(12):3218-24.

2. Carrillo A, et al. J Virol. 1998 Sep;72(9):7532-41.

Lopinavir (ABT-378, ABT378)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Lopinavir (ABT-378, ABT378)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.