Lonitoclax

Chemical Structure : Lonitoclax

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货号: PC-24151Not For Human Use, Lab Use Only.

Lonitoclax is a potent, selective next generation BCL-2 inhibitor, a key pro-survival protein that is overexpressed in many cancers, for the treatment of AML and CLL.

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Lonitoclax is a potent, selective next generation BCL-2 inhibitor, a key pro-survival protein that is overexpressed in many cancers, for the treatment of AML and CLL.

物理化学性质&存储条件

分子量	733.31
分子式	C43H45ClN4O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-5-(5-chloro-2-(3-(morpholinomethyl)-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)phenyl)-N-(4-hydroxyphenyl)-N-(3-methoxy-2-methylbenzyl)-1,2-dimethyl-1H-pyrrole-3-carboxamide

参考文献

1. Patent WO2023129553 A1.

Lonitoclax

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物理化学性质&存储条件

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Lonitoclax

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物理化学性质&存储条件

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