LolCDE-IN-1

Chemical Structure : LolCDE-IN-1

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货号: PC-23141Not For Human Use, Lab Use Only.

LolCDE-IN-1 is a small molecule antibacterial agent targeting the ABC transporter complex LolCDE, inhibits bacterial growth by targeting LolCDE to block lipoprotein transport to the outer membrane.

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生物&药学活性

LolCDE-IN-1 is a small molecule antibacterial agent targeting the ABC transporter complex LolCDE, inhibits bacterial growth by targeting LolCDE to block lipoprotein transport to the outer membrane.
LolCDE-IN-1 inhibits E. coli ATCC 25922 and E. coli ATCC 25922 ΔtolCwith MIC with 8 μg/ml and 0.125 μg/ml.

物理化学性质&存储条件

分子量	345.38
分子式	C21H16FN3O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(3-(3-((4-Fluorobenzyl)oxy)phenyl)-1H-pyrazol-4-yl)pyridine

参考文献

1. Nayar AS, et al. J Bacteriol. 2015 May;197(10):1726-34.

LolCDE-IN-1

生物&药学活性

物理化学性质&存储条件

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LolCDE-IN-1

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物理化学性质&存储条件

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