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Lisavanbulin dihydrochloride

Chemical Structure : Lisavanbulin dihydrochloride

CAS No.: 1387574-54-0

Lisavanbulin dihydrochloride (BAL-101553 dihydrochloride)

货号: PC-23206Not For Human Use, Lab Use Only.

Lisavanbulin dihydrochloride (BAL101553) is a microtubule-destabilizing drug, binds to the colchicine site of tubulin, is the prodrug of the microtubule targeting agent Avanbulin (BAL27862).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Lisavanbulin dihydrochloride (BAL101553) is a microtubule-destabilizing drug, binds to the colchicine site of tubulin, is the prodrug of the microtubule targeting agent Avanbulin (BAL27862).

物理化学性质&存储条件

分子量 588.49
分子式 C26H31Cl2N9O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(2S)-2,6-Diamino-N-[4-[2-[2-[4-[(2-cyanoethyl)amino]-1,2,5-oxadiazol-3-yl]-1H-benzimidazol-1-yl]acetyl]phenyl]hexanamide dihydrochloride

参考文献

1. Prota AE, et al. J Mol Biol. 2014 Apr 17;426(8):1848-60.

2. Kolb EA, et al. Pediatr Blood Cancer. 2015 Jun;62(6):1106-9.

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