Lificiguat |CAS:170632-47-0 Probechem Biochemicals

Chemical Structure : Lificiguat

CAS No.: 170632-47-0

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Lificiguat (YC-1;YC 1)

货号: PC-44126Not For Human Use, Lab Use Only.

Lificiguat (YC-1) is an NO-independent, superoxide-sensitive stimulator of sGC (soluble guanylyl cyclase) with EC50 of 18.6 uM.

规格	价格	库存
5 mg (Free Sample)	￥280	In stock
25 mg	￥1480	In stock
50 mg	￥2380	In stock
100 mg	￥3980	In stock
250 mg		Get quote

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生物&药学活性

Lificiguat (YC-1) is an NO-independent, superoxide-sensitive stimulator of sGC (soluble guanylyl cyclase) with EC50 of 18.6 uM.
YC-1 elicits only minor effects on relaxation and cyclic GMP, increases the vasodilator potency of SNP and nitroglycerin (NTG) by 10 fold.
YC-1 markedly enhances SNP- and NTG-induced cyclic GMP formation at 3 uM.

物理化学性质&存储条件

分子量	304.3425
分子式	C19H16N2O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: ≥ 51 mg/mL
Chemical Name/SMILES	2-Furanmethanol, 5-[1-(phenylmethyl)-1H-indazol-3-yl]-

参考文献

1. Mülsch A, et al. Br J Pharmacol. 1997 Feb;120(4):681-9.

2. Purohit R, et al. Biochemistry. 2014 Jan 14;53(1):101-14.

3. Friebe A, et al. Mol Pharmacol. 1998 Jan;53(1):123-7.

Lificiguat (YC-1;YC 1)

生物&药学活性

物理化学性质&存储条件

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Lificiguat (YC-1;YC 1)

生物&药学活性

物理化学性质&存储条件

参考文献

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