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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Aldose Reductase-Lidorestat
Lidorestat

Chemical Structure : Lidorestat

CAS No.: 245116-90-9

Lidorestat (IDD-676, IDD676)

货号: PC-25941Not For Human Use, Lab Use Only.

Lidorestat (IDD-676) is a potent, selective and orally active aldose reductase inhibitor with IC50 of 5 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Lidorestat (IDD-676) is a potent, selective and orally active aldose reductase inhibitor with IC50 of 5 nM.

物理化学性质&存储条件

分子量 376.35
分子式 C18H11F3N2O2S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(3-((4,5,7-Trifluorobenzo[d]thiazol-2-yl)methyl)-1h-indol-1-yl)acetic acid

参考文献

1. Noh HL, et al. J Pharmacol Exp Ther. 2009 Feb;328(2):496-503.

2. Maccari R, et al. Bioorg Med Chem. 2010 Jun 1;18(11):4049-55.

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