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首页-小分子抑制剂&激动剂-GPCR-Neurotensin Receptor-Levocabastine hydrochloride
Levocabastine hydrochloride

Chemical Structure : Levocabastine hydrochloride

CAS No.: 79547-78-7

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Levocabastine hydrochloride (R 50547)

货号: PC-26998Not For Human Use, Lab Use Only.

Levocabastine hydrochloride (R 50547) is a potent and selective histamine H1-receptor (H1R) antagonist, is also a selective, high affinity neurotensin receptor subtype 2 (NTSR2, NTS2) antagonist with Ki of 17 nM for mNTRS2.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Levocabastine hydrochloride (R 50547) is a potent and selective histamine H1-receptor (H1R) antagonist, is also a selective, high affinity neurotensin receptor subtype 2 (NTSR2, NTS2) antagonist with Ki of 17 nM for mNTRS2.

物理化学性质&存储条件

分子量 456.99
分子式 C26H30ClFN2O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(3S,4R)-1-((1s,4R)-4-cyano-4-(4-fluorophenyl)cyclohexyl)-3-methyl-4-phenylpiperidine-4-carboxylic acid hydrochloride

参考文献

1. Folkerts G, et, al. Br J Pharmacol. 1993 Apr;108(4):1083-93.

2. Qasem AR, et, al. Biochem Pharmacol. 2008 Sep 15;76(6):751-62.

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