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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-Nucleoside Antimetabolite/Analog-Leucovorin
Leucovorin

Chemical Structure : Leucovorin

CAS No.: 58-05-9

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Leucovorin (Folinic acid)

货号: PC-26912Not For Human Use, Lab Use Only.

Leucovorin (folinic acid, calcium folinate) is a prescription form of reduced folic acid that does not require enzymatic activation by dihydrofolate reductase (DHFR), prevents side effects from certain medications, such as methotrexate.

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50 mg ￥380 In stock
100 mg ￥580 In stock
500 mg Get quote
1 g Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Leucovorin (folinic acid, calcium folinate) is a prescription form of reduced folic acid that does not require enzymatic activation by dihydrofolate reductase (DHFR), prevents side effects from certain medications, such as methotrexate.

物理化学性质&存储条件

分子量 473.45
分子式 C20H23N7O7
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(4-(((2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzoyl)-L-glutamic acid

参考文献

1. Goldman ID, et al. NCI Monogr. 1987;(5):17-26.

2. Rosowsky A, et al. Biochem Pharmacol. 1989 Aug 15;38(16):2677-84.

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