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首页-抗体和重组蛋白-Biosimilar Antibody-Leramilimab
Leramilimab

Chemical Structure : Leramilimab

CAS No.:

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Leramilimab (Anti-human LAG3 mAb, human IgG4P-Kappa; LAG-525; IMP701)

货号: PC-Ab1102Not For Human Use, Lab Use Only.

LAG525 (Leramilimab) is a high-affinity, ligand-blocking monoclonal antibody that targets LAG3 and blocks interaction with MHC class II molecules, leading to enhanced T-cell response to tumor cells and decreased tumor growth. LAG525 blocks binding of LAG-3, a negative regulator of T-cell signalling, to MHC class II on tumour cells, which renders the tumour microenvironment less immunosuppressive, and may therefore enhance the activity of PD-1 blockade..

规格 价格 库存 数量
1 mg ￥3580 In stock
5 mg ￥7580 In stock
10 mg ￥12800 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

LAG525 (Leramilimab) is a high-affinity, ligand-blocking monoclonal antibody that targets LAG3 and blocks interaction with MHC class II molecules, leading to enhanced T-cell response to tumor cells and decreased tumor growth. LAG525 blocks binding of LAG-3, a negative regulator of T-cell signalling, to MHC class II on tumour cells, which renders the tumour microenvironment less immunosuppressive, and may therefore enhance the activity of PD-1 blockade.

物理化学性质&存储条件

分子量
分子式 Human IgG4P-Kappa
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

PBS, pH 7.0 Contains no stabilizers or preservatives
Chemical Name/SMILES

Leramilimab; LAG525; LAG-525; IMP701; IMP-701; Anti-Lymphocyte Activation Gene 3; Lag3 protein; Anti-human lymphocyte activation 3 protein; Anti-human LAG-3; Anti-human CD223

参考文献

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