Leonurine |CAS:24697-74-3 Probechem Biochemicals

Chemical Structure : Leonurine

CAS No.: 24697-74-3

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Leonurine (SCM-198, SCM198)

货号: PC-62213Not For Human Use, Lab Use Only.

Leonurine (SCM-198) is a natural alkaloid that exhibits cardio-and neuronal-protective effects both in vitro and in vivo, occupies the caspase recruitment site of Apaf-1, blocks its interaction with procaspase-9.

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10 mg	￥980	In stock
25 mg	￥1680	In stock
50 mg	￥2780	In stock
100 mg		Get quote

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生物&药学活性

Leonurine (SCM-198) is a natural alkaloid that exhibits cardio-and neuronal-protective effects both in vitro and in vivo, occupies the caspase recruitment site of Apaf-1, blocks its interaction with procaspase-9.
Leonurine (SCM-198) attenuates doxorubicin-induced apoptosis in H9c2 cardiac muscle cells, protects middle cerebral artery occluded rats through antioxidant effect and regulation of mitochondrial function, attenuates myocardial fibrotic response via inhibition of NADPH oxidase 4 (Nox4).

物理化学性质&存储条件

分子量	311.338
分子式	C14H21N3O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Benzoic acid, 4-hydroxy-3,5-dimethoxy-, ester with (4-hydroxybutyl)guanidine (8CI)

参考文献

1. Loh KP, et al. Stroke. 2010 Nov;41(11):2661-8.

2. Xin H, et al. Eur J Pharmacol. 2009 Jun 10;612(1-3):75-9.

3. Liu XH, et al. Free Radic Biol Med. 2013 Jan;54:93-104.

4. Wang Y, et al. Sci Rep. 2016 Jul 22;6:29820.

Leonurine (SCM-198, SCM198)

生物&药学活性

物理化学性质&存储条件

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Leonurine (SCM-198, SCM198)

生物&药学活性

物理化学性质&存储条件

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