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首页-抗体和重组蛋白-Biosimilar Antibody-Lemzoparlimab
Lemzoparlimab

Chemical Structure : Lemzoparlimab

CAS No.:

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Lemzoparlimab (Anti-human CD47 mAb, human IgG1-Kappa; TJC4; TJ 011133)

货号: PC-Ab1062Not For Human Use, Lab Use Only.

Lemzoparlimab (TJ011133 or TJC4) is a fully human, anti-CD47 IgG4 antibody that is endowed with a red blood cell (RBC) sparing property and unique binding epitope, potentially differentiating itself from other CD47 axis targeting therapies. Lemzoparlimab blocks the interaction of CD47 and SIRPα, leading to phagocytosis of various CD47+ tumor cell lines and primary AML cells..

规格 价格 库存 数量
1 mg ￥3580 In stock
5 mg ￥7580 In stock
10 mg ￥12800 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Lemzoparlimab (TJ011133 or TJC4) is a fully human, anti-CD47 IgG4 antibody that is endowed with a red blood cell (RBC) sparing property and unique binding epitope, potentially differentiating itself from other CD47 axis targeting therapies. Lemzoparlimab blocks the interaction of CD47 and SIRPα, leading to phagocytosis of various CD47+ tumor cell lines and primary AML cells.

物理化学性质&存储条件

分子量
分子式 Human IgG1-Kappa
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

PBS, pH 7.0 Contains no stabilizers or preservatives
Chemical Name/SMILES

Lemzoparlimab; TJC4; TJC 4; TJ 011133; Anti-human Leukocyte surface antigen CD47; Cluster of differentiation 47; CD47 Antigen (Rh-Related Antigen, Integrin-Associated Signal Transducer)

参考文献

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