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首页-小分子抑制剂&激动剂-Others-Other Targets-Leflunomide
Leflunomide

Chemical Structure : Leflunomide

CAS No.: 75706-12-6

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Leflunomide (HWA486, RS-34821, SU101)

货号: PC-22222Not For Human Use, Lab Use Only.

Leflunomide is a potent dihydroorotate dehydrogenase (DHODH) and pyrimidine synthesis inhibitor with IC50 of 208.5 nM in cell-free human DHODH enzyme inhibition assays.

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50 mg ￥580 In stock
100 mg ￥880 In stock
250 mg ￥1380 In stock
500 mg ￥2280 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Leflunomide is a potent dihydroorotate dehydrogenase (DHODH) and pyrimidine synthesis inhibitor with IC50 of 208.5 nM in cell-free human DHODH enzyme inhibition assays.

物理化学性质&存储条件

分子量 270.21
分子式 C12H9F3N2O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

5-Methyl-N-(4-(trifluoromethyl)phenyl)isoxazole-4-carboxamide

参考文献

1. Ola A Elgamal, et al. JCI Insight. 2024 Apr 22;9(8):e173646.

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