Leelamine hydrochloride |CAS:16496-99-4 Probechem Biochemicals

Chemical Structure : Leelamine hydrochloride

CAS No.: 16496-99-4

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Leelamine hydrochloride (Dehydroabietylamine)

货号: PC-35497Not For Human Use, Lab Use Only.

Leelamine hydrochloride (Dehydroabietylamine) is a novel inhibitor of androgen receptor (AR), inhibits castration-resistant prostate cancer cells.

规格	价格	库存
10 mg	￥1180	In stock
25 mg	￥1980	In stock
100 mg	￥4980	In stock
500 mg		Get quote

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生物&药学活性

Leelamine hydrochloride (Dehydroabietylamine) is a novel inhibitor of androgen receptor (AR), inhibits castration-resistant prostate cancer cells; causes apoptosis and suppresses 22Rv1 xenograft growth in vivo; Leelamine mediates cancer cell death through inhibition of intracellular cholesterol transport.

物理化学性质&存储条件

分子量	321.933
分子式	C20H32ClN
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1R,2,3,4,4aS,9,10,10aR-octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenemethanamine, monohydrochloride

参考文献

1. Singh KB, et al. Mol Cancer Ther. 2018 Jul 20. pii: molcanther.0117.2018.

2. Gowda R, et al. Oncotarget. 2017 Apr 25;8(17):28260-28277.

3. Sehrawat A, et al. Mol Carcinog. 2017 Feb;56(2):337-348.

4. Kuzu OF, et al. Mol Cancer Ther. 2014 Jul;13(7):1690-703.

Leelamine hydrochloride (Dehydroabietylamine)

生物&药学活性

物理化学性质&存储条件

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Leelamine hydrochloride (Dehydroabietylamine)

生物&药学活性

物理化学性质&存储条件

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