LasR inhibitor 2g

Chemical Structure : LasR inhibitor 2g

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货号: PC-28637Not For Human Use, Lab Use Only.

LasR inhibitor 2g is a potent, small molecule inhibitor of P. aeruginosa QS hierarchy LasR, demonstrated exceptional biofilm inhibition with IC50 of 0.14 uM, binds LasR with high affinity (KD=38.97 uM), suppresses LasR-regulated virulence pathways, reduces pyocyanin production and bacterial motility, shows synergistic antibiotic enhancement activity.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

物理化学性质&存储条件

分子量	324.26
分子式	C15H11F3N2O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(3-nitrophenyl)-N-(3-(trifluoromethyl)phenyl)acetamide

参考文献

1. Huang Y, et al. Acta Pharm Sin B. 2026 Oct;16(10):6852-6874.