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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Bacterial-LasR-IN-6
LasR-IN-6

Chemical Structure : LasR-IN-6

CAS No.: 872546-39-9

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LasR-IN-6

货号: PC-28636Not For Human Use, Lab Use Only.

LasR-IN-6 (Cpmpound 7d) is a potent quorum sensing (QS) system LasR inhibitor with IC50 of 0.261 uM, has MIC of 62.5 uM against P. aeruginosa PAO1, significantly suppressed key virulence factors, including protease production, biofilm formation, and motility phenotypes in P. aeruginosa.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

LasR-IN-6 (Cpmpound 7d) is a potent quorum sensing (QS) system LasR inhibitor with IC50 of 0.261 uM, has MIC of 62.5 uM against P. aeruginosa PAO1, significantly suppressed key virulence factors, including protease production, biofilm formation, and motility phenotypes in P. aeruginosa.

物理化学性质&存储条件

分子量 469.46
分子式 C25H19N5O5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-(4-(2-(1H-benzo[d]imidazol-2-yl)-2-cyanovinyl)-2-methoxyphenoxy)-N-(4-nitrophenyl)acetamide

参考文献

1. Mohammed EZ, et al. Bioorg Chem. 2026 Sep 15;180:110160.

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