Larazotide acetate (AT1001) | Zonulin inhibitor | Probechem Biochemicals

Chemical Structure : Larazotide acetate

CAS No.: 881851-50-9

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Larazotide acetate (AT1001, INN-202, GGVLVQPG acetate)

货号: PC-49429Not For Human Use, Lab Use Only.

Larazotide acetate (AT1001) is a synthetic, competitive octapeptide inhibitor of zonulin, acts as a tight junction regulator to restore intestinal barrier function.

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5 mg	￥880	In stock
10 mg	￥1280	In stock
25 mg	￥2180	In stock
50 mg	￥3580	In stock
100 mg		Get quote

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生物&药学活性

Larazotide acetate (AT1001) is a synthetic, competitive octapeptide inhibitor of zonulin, acts as a tight junction regulator to restore intestinal barrier function.
Larazotide acetate specifically increases intestinal barrier integrity, effectively reduces arthritis onset.
Larazotide acetate decreases plasma SARS-CoV-2 spike antigen levels and inflammatory markers in multisystem inflammatory syndrome in children (MIS-C).
Larazotide acetate binds SARS-CoV-2 Mpro catalytic domain.

物理化学性质&存储条件

分子量	785.89
分子式	C34H59N9O12
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Glycine, glycylglycyl-L-valyl-L-leucyl-L-valyl-L-glutaminyl-L-prolyl-, acetate (1:1)

参考文献

1. Tajik N, et al. Nat Commun. 2020 Apr 24;11(1):1995.

2. Benjamin ER, et al. Mol Ther. 2012 Apr;20(4):717-26.

3. Di Micco S, et al. Int J Mol Sci. 2021 Aug 30;22(17):9427.

4. M C Arrieta, et al. Gut. 2009 Jan;58(1):41-8.

Larazotide acetate (AT1001, INN-202, GGVLVQPG acetate)

生物&药学活性

物理化学性质&存储条件

参考文献

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Larazotide acetate (AT1001, INN-202, GGVLVQPG acetate)

生物&药学活性

物理化学性质&存储条件

参考文献

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