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首页-小分子抑制剂&激动剂-Others-Other Targets-Lalistat-1
Lalistat-1

Chemical Structure : Lalistat-1

CAS No.: 501104-16-1

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Lalistat-1

货号: PC-20890Not For Human Use, Lab Use Only.

Lalistat 1 is a potent and selective lysosomal acid lipase (LAL) inhibitor with IC50 of 68 nM, shows no significant activity against pancreatic lipase or lipoprotein lipase.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Lalistat 1 is a potent and selective lysosomal acid lipase (LAL) inhibitor with IC50 of 68 nM, shows no significant activity against pancreatic lipase or lipoprotein lipase.
Lalistat 1 interferes with neutral lipolysis.
Lalistat 1 binds to active center of neutral lipid hydrolases.

物理化学性质&存储条件

分子量 298.36
分子式 C12H18N4O3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

O=C(OC1=NSN=C1N2CCCCC2)N3CCOCC3

参考文献

1. Bradić I, et al. Mol Metab. 2022 Jul;61:101510.

2. Hamilton J, et al. Clin Chim Acta. 2012 Aug 16;413(15-16):1207-10.

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